Up to 15 cm of snow is forecast to fall across much of the NWT on Wednesday night and into Thursday, Environment Canada declared.
The agency's snowfall warning, posted on Wednesday afternoon, suggested snow would begin on Wednesday night in the Dehcho then reach the North Slave and South Slave by Thursday morning.
Residents should expect "the heaviest accumulations occurring by Thursday evening," federal forecasters said.
"Light snow will linger through Friday morning with storm total amounts in the 10 to 15 cm range," the warning added.
Gusty winds are also forecast, meaning visibility in blowing snow is likely to be severely reduced.
"Prepare for quickly changing and deteriorating travel conditions. Visibility may be suddenly reduced at times," Environment Canada cautioned.
The snowfall warning extends to Fort Liard, Fort Simpson, Fort Providence, Yellowknife, Hay River, Fort Resolution, and Fort Smith.
Meanwhile, much of the Beaufort Delta faces an extreme cold warning as temperatures drop.
Wind chills are forecast to dip below -50C overnight in Aklavik, Fort McPherson, Tsiigehtchic, Inuvik, and Tuktoyaktuk. Behchokǫ̀, Whatì, and Wekweètì are also under extreme cold warnings.